Hajos-Parrish ketone: approaches toward C-ring prcursors of 7-deoxytaxol

Lajunen, M.; Koskinen, A.

Aaltodoc
→
6b Artikkelit / Articles from Research information portal
→
[article-cris] Kemian tekniikan korkeakoulu / CHEM
→
View Item

dc.contributor	Aalto-yliopisto	fi
dc.contributor	Aalto University	en
dc.contributor.author	Lajunen, M.
dc.contributor.author	Koskinen, A.
dc.date.accessioned	2016-09-23T08:16:42Z
dc.date.issued	2000
dc.identifier.citation	Lajunen , M & Koskinen , A 2000 , ' Hajos-Parrish ketone: approaches toward C-ring prcursors of 7-deoxytaxol ' , Journal of the Chemical Society, Perkin Transactions 1 , no. 1 , pp. 1439-1443 . https://doi.org/10.1039/a909471g	en
dc.identifier.other	PURE UUID: 8896995d-4bef-429a-83d7-6388a25cc00d
dc.identifier.other	PURE ITEMURL: https://research.aalto.fi/en/publications/8896995d-4bef-429a-83d7-6388a25cc00d
dc.identifier.other	PURE FILEURL: https://research.aalto.fi/files/7159156/ms076.PDF
dc.identifier.uri	https://aaltodoc.aalto.fi/handle/123456789/22321
dc.description.abstract	Two routes were evaluated for the preparation of multiply functionalized cyclohexane derivatives in a stereocontrolled fashion from readily available Hajos–Parrish ketone 1. Reduction (catalytic or dissolving metal) led to the cis-isomer 8, in stark contrast to previous literature. Finally, modification of earlier steroid chemistry allowed the synthesis of the trans-isomer 14. The latter is a useful intermediate for the synthesis of 7-deoxytaxol derivatives.	en
dc.format.extent	1439-1443
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	Journal Chem. Soc., Perkin Trans.	en
dc.relation.ispartofseries	issue 1	en
dc.rights	openAccess	en
dc.title	Hajos-Parrish ketone: approaches toward C-ring prcursors of 7-deoxytaxol	en
dc.type	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä	fi
dc.description.version	Peer reviewed	en
dc.contributor.department	Department of Chemistry	en
dc.subject.keyword	synthesis
dc.subject.keyword	taxol
dc.identifier.urn	URN:NBN:fi:aalto-201609234325
dc.identifier.doi	10.1039/a909471g
dc.type.version	acceptedVersion